[Folding@home] Meet the classic paper: Sorin and Pande 2005

[BOINC_News]

Now that Folding@home has turned 21, we are revisiting some classic papers from the team that have had significant scientific impacts. Sorin and Pande (2005) describes simulations of alpha-helix folding: i.e. the helix-coil transition. Exploring the helix-coil transition via all-atom equilibrium ensemble simulations EJ Sorin, VS Pande Biophysical journal 88 (4), 2472-2493 Why is this work important? When Folding@home (FAH) debuted in 2000, the new insight it promised was an ability to observe rare folding events through parallel, crowdsourced simulations. This paper focused more on the unprecedented...

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