[Folding@home] 2020 in review, and happy new year 2021!
Posted: Mon Jan 04, 2021 11:04 pm
TL;DR: During 2020, Folding@home was like the citizens’ fleet in the movie Star Wars: The Rise of Skywalker. Everyone came together to face a common foe, in this case the SARS-CoV-2 virus responsible for the COVID-19 pandemic. We are extremally grateful to everyone who joined in the fight, helping us to discover new antiviral candidates now in animal testing and publish four papers so far: 1) SARS-CoV-2 Simulations Go Exascale to Capture Spike Opening and Reveal Cryptic Pockets Across the Proteome, 2) SARS-CoV-2 Nsp16 activation mechanism and a cryptic pocket with pan-coronavirus antiviral potential, 3) The SARS-CoV-2 nucleocapsid protein is dynamic, disordered, and phase separates with RNA, 4) COVID...
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