[Folding@home] Happy 2026! (belated)

[BOINC_News]

Thanks to everyone who helped get a lot of great science done in 2025! We’re looking forward to a great 2026 with you!

First, the good stuff!

Folding@home is continuing to provide insight into diseases from cancer to Ebola infections that point the way to new therapeutics.

For example, Qiu and co-authors used Folding@home simulations to identify new ways of drugging a protein called KRas that is one of the most prominent players in cancer. They found stable conformations of Kras adjacent to another rprotein that could be stabilized with a drug called a PROTAC that triggers degradation of a target protein (in this case Kras). Building on this insight could be really valuable for combating a broad range of cancers.

Bhattacharjee and co-workers also made progress on BRCA1, one of the most important players in breast cancer. They explained how...


Read more